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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK8
All Species:
0.91
Human Site:
S632
Identified Species:
1.54
UniProt:
Q86SG6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86SG6
NP_835464.1
692
74806
S632
T
V
A
I
G
A
E
S
E
V
Y
S
W
G
K
Chimpanzee
Pan troglodytes
XP_511801
843
90571
G783
T
V
A
I
G
A
E
G
E
V
Y
S
W
G
K
Rhesus Macaque
Macaca mulatta
XP_001106986
781
84378
G721
T
V
A
I
G
A
E
G
E
V
Y
S
W
G
K
Dog
Lupus familis
XP_548291
727
78319
G667
T
V
A
V
G
A
E
G
E
V
Y
S
W
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZR4
698
75246
G638
T
V
A
V
G
A
E
G
E
V
Y
S
W
G
K
Rat
Rattus norvegicus
NP_001099274
698
75236
G638
T
V
A
I
G
A
E
G
E
V
Y
S
W
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512532
832
89432
G616
T
V
A
I
G
A
D
G
E
V
Y
T
W
G
K
Chicken
Gallus gallus
XP_415822
728
79098
G638
T
V
A
I
G
A
D
G
E
V
C
T
W
G
K
Frog
Xenopus laevis
Q7ZZC8
944
104521
N651
T
T
A
A
T
A
D
N
H
I
F
A
W
G
N
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
G637
T
L
A
I
G
A
E
G
E
V
Y
T
W
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490968
998
111830
E909
V
R
F
D
D
S
C
E
K
L
K
I
M
D
A
Sea Urchin
Strong. purpuratus
XP_001201534
446
48490
L399
G
R
G
D
N
G
R
L
G
L
D
S
Q
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
S559
L
E
G
L
L
E
F
S
A
R
L
L
Q
D
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
A733
S
A
I
I
S
N
E
A
K
L
R
A
F
K
E
Conservation
Percent
Protein Identity:
100
75.4
87
88.8
N.A.
93.5
93.4
N.A.
68.7
76.9
24.7
73.8
N.A.
N.A.
N.A.
23.2
38.2
Protein Similarity:
100
76.9
87.8
91
N.A.
96.4
95.4
N.A.
74
85.1
39.5
85.2
N.A.
N.A.
N.A.
37.8
50.8
P-Site Identity:
100
93.3
93.3
86.6
N.A.
86.6
93.3
N.A.
80
73.3
33.3
80
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
66.6
93.3
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
N.A.
21.7
Protein Similarity:
N.A.
N.A.
N.A.
44
N.A.
37.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
72
8
0
72
0
8
8
0
0
15
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
15
8
0
22
0
0
0
8
0
0
15
0
% D
% Glu:
0
8
0
0
0
8
58
8
65
0
0
0
0
8
15
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
8
0
8
0
0
% F
% Gly:
8
0
15
0
65
8
0
58
8
0
0
0
0
72
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
58
0
0
0
0
0
8
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
15
0
8
0
0
8
65
% K
% Leu:
8
8
0
8
8
0
0
8
0
22
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% Q
% Arg:
0
15
0
0
0
0
8
0
0
8
8
0
0
0
0
% R
% Ser:
8
0
0
0
8
8
0
15
0
0
0
50
0
0
8
% S
% Thr:
72
8
0
0
8
0
0
0
0
0
0
22
0
0
0
% T
% Val:
8
58
0
15
0
0
0
0
0
65
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
72
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
58
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _